Use this slide to introduce the major brain regions involved in mood regulation. Point to each highlighted area, describe its function, and relate it to depression and anxiety symptoms. Invite participants to note any questions about structure–function links.

Use this slide to introduce the key neurotransmitter systems involved in mood regulation. Walk participants through each pathway, noting origin nuclei, projection targets, and functional roles. Ask learners how alterations in these systems might contribute to symptoms of depression and anxiety.

Explain the role of SERT in terminating serotonergic signals and how SSRIs competitively inhibit this transporter. Show how increased synaptic serotonin modulates mood circuits.

Discuss why patients may not feel immediate relief even though serotonin levels rise quickly. Emphasize the importance of autoreceptor adaptation and neuroplasticity.

Highlight the need for patient counseling on side effects and adherence. Encourage discussion on how to manage common adverse effects and the importance of communication.

Wrap up the SSRI section, reiterating how understanding SSRI mechanisms can reduce stigma and empower informed discussions about mental health treatments.